Currently Published Papers in Green Chemistry

Green Nanotechnology in Herbal Medicine and Ayurveda

Revika Arora,DOI: 10.24214/IJGHC/GC/7/4 /74959.

Green Nanotechnology is the study of how nanotechnology can benefit the environment, such as by using less energy during the manufacturing process, the ability to recycle products after use, and using eco-friendly materials. Nanotechnology covers the diverse area of matters at dimensions between approximately 1 to 100 nanometers.  Herbal medicines have been widely used all over the world since ancient times and have been recognized by physicians and patients for their better therapeutic value as they have fewer adverse effects as compared with modern medicines.  Phytotherapeutics need a scientific approach to deliver the components in a sustained manner to increase patient compliance and avoid repeated administration. This can be achieved by designing novel drug delivery systems (NDDS) for herbal constituents. The integration of the nanoscience as a NDDS in traditional system of medicine enriches the potential of herbal drugs for treating chronic diseases.  Ayurveda   is thousands of years old holistic system of Indian medicine. Various herbs, metals and non-metal preparations are used as medicine in Ayurveda.  This review paper opens door to a completely new dimension in herbal medicine and ayurveda using green nanotechnology.

Qualitative phytochemical constituents assay of diverse solvent extracts of chosen medicinal plants

Kokkaiah Irulandi and Vadivel Siva,DOI: 10.24214/IJGHC/GC/7/4 /74148

Preliminary phytochemical analysis was important way for identified number of compounds in the chosen plant extracts and developments new drugs in the pharmaceutical fields. Phytochemical screening of three chosen plant extracts were contain following valuable constituents like quinones, coumarins, phenols, flavonoids, tannins, catechins, alkaloids, terpenoids and saponins using standard methods. Both methanol and aqueous extract of all tested medicinal plants were found to contain alkaloids. Phenols revealed in the methanol extracts of all the tested plants. Whole plant extract of Coscinium fenestratum revealed positive result for coumarins except methanol solvent extract. The entire tested extract of Atalantia racemosa showed negative for coumarins. The assays of all the plant methanol extracts were found flavonids compounds. In my study revealed that methanol and aqueous extracts of chosen plants contain bioavailability compounds and they are valid useful to treat various illness.

Reduction of Schiff Bases from 5-Bromo-salicyaldehyde and Study of their Antimicrobial Activity

C. A. Nehete and C. J. Patil,DOI: 10.24214/IJGHC/GC/7/4 /72540.

The compounds containing >C=N- were synthesized by reacting 5-bromo-2-hydroxy benzaldehyde with aniline and substituted aromatic anilines are mixed separately and were refluxed in ethanol, till to complete the reaction, which was further reduced by NaBH4 and ascertain by TLC, the mobile phase, ethyl acetate: n-hexane (2.5: 0.5) was used for TLC. The final products were analyzed and characterized by visual viz. nature and colour, physical viz. m. p., analytical viz. TLC, instrumental viz. UV-Vis, FTIR and HR-MS spectral technique.

Secondary metabolites from the plant Manilkara hexandra Roxb

T.Annamalai John Joel Ganadoss Ayyar Manikandan and A.A.M. Prince,DOI: 10.24214/IJGHC/GC/7/4 /71524.

The air dried leaves of folklore medicinal plant, Manilkara hexandra Roxb., yielded Five known compounds: 4-methyl benzaldehyde (1), Cinnamic acid (2), Methyl-p-coumarate (3), p-coumaric acid (4), 3,4-dihydroxy benzaldehyde (5). The air dried flowers of the plant yielded two known compounds: Ethyl nicotinate (6) and D-Quercitol (7). Structure of the compounds was elucidated on the basis of spectroscopic analysis (UV, IR, 1H & 13C NMR and Mass) and Co-TLC comparison with an authentic samples and literature data. Benzaldehyde derivatives are reported for the first time from this plant. One of the compounds (5) is active against Streptococcus aureus at 500µg/ml level with zone of inhibition of 21.5±0.70mm and another compound (3) is active against Streptococcus epidermidis at 250µg/ml level with zone of inhibition of 22±1.41mm. Our finding throws light into the wisdom of our ancient system of medicine/practices, regular use of this herb in our daily routine can provide dynamic skin barrier against opportunistic infections.

Electroanalytical characterization of Nimesulide by Differential Pulse Polarography: Application to Pharmaceutical analysis

Patil S. V*, Kashid L. M., Kolekar G. B., Valekar N. J. and Tamhankar B. V,DOI: 10.24214/IJGHC/GC/7/4 /70114.

: In the present investigation electroanalytical characterization of Nimesulide were carried out. Differential pulse polarographic technique was used for the characterization of Nimesulide. The optimum experimental parameters for the differential pulse polarography (DPP) method were 0.1 M NaOH as the supporting electrolyte, current range 10µA, data acquisition fast, scan rate 6mV/sec, drop time 1sec, scan type forward, pulse amplitude 50mV. The calibration curves for Nimesulide were linear with the limit of detection (LOD) 5.02X 10-6 M obtained by the DPP method.