S.V.P Easwari, Dr B Vasanthakumari, Dr. N Vijayakumar, Dr. P.A Mary Helen; IJGHC, December 2017 – February 2018; Sec. A; Vol.7, No.1, 153-166.; DOI: 10.24214/IJGHC/GC/7/1/15366
The present study was undertaken to investigate the invitro anticancer, antibacterial and larvicidal activity of different solvent extracts of Annona muricata. Colon cancer often occurs for unknown reasons. The cytotoxic activity of fresh chloroform extract of Annona muricata was evaluated on HT 29 colon cancer cell line using neutral red assay method. The 50% inhibition of cell growth (IC50) value of the extract for HT 29 cancer cell line was 100 μg/ml. This result indicated the potential of selective anticancer activity of fresh chloroform extract of Annona muricata leaves. The different extracts showed antibacterial activity against Enterobacter and E.coli with iso amyl alcohol fresh extract showing a zone diameter of 37mm against E.coli and ethyl acetate dark extract showing a zone diameter of 34mm against Enterobacter. The larvicidal activity of fresh aqueous leaf extracts of Annona muricata plant in five different concentration of extract ranging from 2.00 - 10.00 mg/ml showed 100% mortality revealed that the A. muricata extract was highly effective as larvicide against the fourth instar larvae of the mosquito, Aedes aegypti.">
Ravindra D. Kale, Sangeeta Barwar, Prerana Kane, Sandeep More; IJGHC, December 2017 – February 2018; Sec. A; Vol.7, No.1, 143-152.; DOI: 10.24214/IJGHC/GC/7/1/14352
Bio-nanotechnology has emerged as integration between biotechnology and nanotechnology for developing biosynthetic and environmental friendly technology for synthesis of nanomaterials. Magnetite nanoparticles were synthesized by using betel leaves as reducing agent. Reduction of magnetite nanoparticles was confirmed by UV-VIS analysis. Optimization of parameters, temperature and reducing agent concentration was done using RSM as per central composite design (CCD). The nature of the chemical group deposited on the nanoparticles was studied using FT-IR. Particles size estimation was done on TEM and nanoparticle size analyser. The crystallinity of the nanoparticle was found out using XRD.
S.L.Sathya Saibaba, P. Karthiga and K. Swarnalatha;IJGHC, December 2017 – February 2018; Sec. A; Vol.7, No.1, 130-142.;DOI: 10.24214/IJGHC/GC/7/1/13042
Schiff base of o-phenylenediamine was synthesized and characterized by elemental analyses, H-NMR, ESI-Mass, FT-IR and UV-Vis spectroscopy. The antibacterial activity of the Schiff base was screened against four Gram-positive bacteria, viz. Staphylococcus aureus, Bacillus cereus, Mycobacterium tuberculosis, streptococcus pneumonia and six Gram-negative bacteria viz. Pseudomonas aeruginosa, Escherichia coli, Enterobacter aerogenes, Klebsiella pneumonia, Salmonella typhi and Salmonella enteric serotype. Anticancer activity of the compound was studied in vitro against two cancer cell lines, human colon adenocarcinoma cancer cell (HT-29) and human breast cancer cell (MCF-7) using the MTT assay. The results demonstrated that treatment with the synthesized compound affected cell viability efficiently towards both HT-29 and MCF-7 cells.
Aamir Numan, Dr. Niaz Ali, Muhammad Ijaz Khan , Mehmood Ur Rehman and Abdul Qadir,IJGHC, December 2017 – February 2018; Sec. A; Vol.7, No.1, 119-129.DOI: 10.24214/IJGHC/GC/7/1/11929.
An experiment to evaluate yield and yield parameters of gram varieties (Chattan and Fahr-e-Thal, Sheen Ghar, KK-1, KK-2) under weeds population was conducted at Agriculture Research station Ahmad Wala Karak during 2014-15. Five treatments were used for evaluation of plant height, numbers of pods per plant, weeds biomass, 100 grain weight, grain yield and cost benefit ratio. The data revealed that treatment and interaction significantly affected all the parameters. Varieties also reach to the level of significant. Two times hand weeding showed significant result in all parameters and was good, suitable, beneficial, and economical for the control of weeds in gram crops. Highest yield of 1392 kg/acre was obtained by two time weeding while lowest yield 869 kg/acre was noted in control. Cost benefit ration also showed that two time weeding is more economical than rest of the treatments. Variety Chattan gave maximum mean yield of 1195 kg/acre while Fakhr-e-Thal gave lowest mean yield of 1121.6 kg/acre
Sanwal Ram, Dr S K Pramanik, Dr Raviraj Singh, Dr Vimla Chowdhary,IJGHC, December 2017 – February 2018; Sec. A; Vol.7, No.1, 114-118.DOI: 10.24214/IJGHC/GC/7/1/11418.
The present study was carried out with the objective of determining the extent of groundwater pollution caused by industrial activity in balotra, barmer district Rajasran which is located at the bank of Luni river. Groundwater Samples were collected from twenty different places, nearby area of Luni River and analysed for the heavy metals and all results were compared with Indian standard specification for drinking water IS 10500(1991). The study reveals that the concentration of major ions exceeding the permissible limit. Groundwater is unsuitable for human consumption as it contains higher concentration of major ions. Contamination of groundwater causes water scarcity for domestic purpose of this study is to highlight the impact of industrial activity on groundwater