Currently Published Papers in Herbal Chemistry

Bioaccumulation Trend Analysis of Insulin Supporting Elements in Anti-diabetic Medicinal Plants and Hierarchal Presentation Based on Decision Tree.

T.S Magili and I.B Bwatanglang,DOI: 10.24214/IJGHC/HC/7/4/40118.

In this study, Elemental Hierarchal Decision Tree’ was developed to aid in the selection of anti-diabetic medicinal plants species on the basis of elemental content preponderance. Instrumental neutron activation analysis (INAA) was used to investigate the bioaccumulation trends of 22 elements in 10 medicinal plants commonly used in Adamawa state, Nigeria for the treatment and management of diabetes mellitus (DM). From the results of the study the essential nutrients such as K, Na, Fe and Co are most effectively translocated by Leptadenia hastata with translocated factor (TF) = 1.51, 1.27, 1.90 and 2.83 respectively. Hymenocardia acida was found to be most effective for majority of the radioactive elements, Sm, Yb, Th, Lu and U with TF = 24.65, 33.46, 82.33 and 25.00 respectively. On the basis of tissue accumulation, the leave of Leptadenia hastata ranked highest in cumulative concentration of elements and Anogeissus leiocarpus ranked highest in cumulative concentration of elements in the stem bark sample. The root bark sample of Jathropha gossypiifolia was ranked highest in cumulative concentration of elements. On the whole, Ca, K and Mg (macro elements) and Cl, Fe, Zn and Mn (micro elements) are the most representatives of essential minerals found in the order of cumulative concentrations in all medicinal plants tissues investigated.

Lantana camara: Ransack of Phytochemical and Pharmacological Aspect

Shyamal K. Jash and Lalan Chandra Mandal,DOI: 10.24214/IJGHC/HC/7/3/36981

India is a gifted country with rich biodiversity and treasure of medicinal plants. From the ancient times various plants have been using for healthcare. Among them, very few were studied systematically so far. Lantana camara is a flowering ornamental and evergreen plant found throughout India. The plant has evoked a lot of interests among the researchers due to its diversified pharmaceutical potential. The Plant is reported to be used in traditional medicine system since very long time for the treatment of various ailments including itches, cuts, ulcers, swellings, bilious fever, cataract, eczema and rheumatism. In last few decades, scientists and researchers have investigated on different parts of the plants. In continuous investigations on this plant, it has been observed that various parts of the plant are used in the treatment of cold, headache, chicken pox, eye injuries, whooping cough, asthma, bronchitis and arterial hypertension. These studies established the therapeutic potential of Lantana camara in modern medicines and considered to be promising candidate for the drug discovery. The current review has deeper focus on Taxonomy, Geographical distribution, phytochemical studies, pharmacological activities and toxicology of Lantana camara.

Hepatoprotective Activity of Methanolic Stem Bark Extract of Parkinsonia aculeata L. in CCl4 Intoxicated Rats

Suneeta Rao, Anil Kumar Sharma, Rajnish Gupta, M.P. Dobhal, M.C. Sharma,DOI: 10.24214/IJGHC/HC/7/3/36068

: Present study evaluated the hepatoprotective action of Parkinsonia aculeata stem-bark methanol extract in CCl4 intoxicated rats. Animals were intraperitoneally administered with CCl4 at1 ml/kg b.wt. once a week for hepatic damage. Oral treatment with P. aculeata methanolic extract at 25, 50 and 100 mg/kg b.wt./day brought about significant normalcy in hepatic tissue injury as well as serum biochemical parameters. Outcome of present study proves the liver rejuvenation potency of P. aculeata which is also supported by strong antioxidant activity of the plant to reduce oxidative stress.

Study of Antioxidant and Aldose Reductase Inhibitory Activity of a weed, Hygrophila ringens (L.) R. Br. ex (Steud.)

T. V. Ramana, O. S. Rathor1,G. Gyananath, Zeyad A. Dahan, G. B. Tiwari4, T.A. Kadam, DOI: 10.24214/IJGHC/HC/7/3/34759

Bioprospecting involves exploration of unidentified species of living organisms for the development of pharmaceuticals, botanical medicines, crop protection agents, cosmetics, horticultural and agricultural seeds, environmental monitoring, manufacturing and construction. With the popularity of bioprospecting for natural compounds, the idea is to elaborate the various chemical components on one of the uncommon plant, Hygrophila ringens (L.) R. Br. ex (Steud.) Acanthaceae family from Marathwada region. In the current study, the phytochemical components were screened in the leaves, flowers and stem of Hygrophila ringens (L.). The analysis revealed  presence of  diverse class of  compounds of therapeutic significance and as speculated the plant extracts exhibited potent antioxidant and ARI activity.  Some of the potential phytochemical compounds may have an important role in these activities.

Harnessing the medicinal importance of Clitoria ternatea for diseases and beyond: a review of its phytochemistry and pharmacology

K. Sharma, R. Bist and ES. Chauhan,DOI: 10.24214/IJGHC/HC/7/3/33646

Clitoria ternatea L generally recognized as Butterfly pea is a traditionally being used Ayurvedic medicine. It is being utilized from centuries to enhance memory and as nootropic, anti-stress, as tranquilizer to relieve anxiety, depression, and convulsion. C. ternatea isolated secondary metabolites include triterpenoids, flavonol glycosides, anthocyanins. It possesses extensive variety of pharmacological actions like fighting against microorganisms, reducing fever, alleviating inflammation and pain, promoting diuresis, controlling diabetes and destroying insects. It is also used as a vascular smooth muscle relaxant. The current review encompasses the bio-active components, pharmacological, phytochemical and toxicity studies of C. ternatea having clinical usage in the Ayurvedic system along with a serious consideration on its future ethno pharmacological potential