Moradali Fouladvand, Soleyman Khorami, Rahim Tahmasebi, Mohsen Khataminejad, DOI: 10.24214/IJGHC/HC/7/4/43445
Our findings show that this method is an efficient, simple and environment- friendly procedure to use the extract of Sargassum oligocystum and Cystoseira trinodis algae against Trichomonas vaginalis in vitro. This work aims phytochemical, HPTLC fingerprint and anti-trichomonas vaginalis screening of Sargassum oligocystum and Cystoseira trinodis with consider green chemistry method. The equoaus, methanol, dichloromethane and n-hexane extracts of the leaves was developed in the mobile phase of Toluene: acetone: formic acid (4.5:4.5:1) using standard procedures and scanned under UV at 254 nm, 366 nm and visible light at 540 nm. The in vitro antiparasite activity was performed on extracts of Sargassum oligocystum and Cystoseira trinodis in water, methanol, dichloromethane and n-hexane against Trichomonas vaginalis.The equeous and organic extracts of the plants at a concentrations of 0.005%, 0.007% and 0.01% were taken and their activities were measured. The results revealed that all the extracts had approximately same degree of antiparasite activity but equeous extract has more advantages than organic extracts due to its low side-effect, environment-friendly, easy and low cost method. HPTLC fingerprint analysis of equeous extract of Sargassum oligocystum and Cystoseira trinodis can be used as a diagnostic tool for the correct identification of the secondry products and it is useful as a phytochemical marker.
Hermano Mascaro Grosso, Maria Teresa Santos, Carlota Saldanha, Ana Silva- Herdade Bibiana Riquelme,DOI: 10.24214/IJGHC/HC/7/4/42633.
Among the numerous plants of medicinal interest is Bauhinia forficata Link, which belongs to the Fabaceae family. Its leaves, branches and roots are widely used in Brazil and Argentina in the form of herbal infusions and other phytotherapeutic preparations for the treatment of various diseases, such as diabetes. The glycemic reduction ability of this medicinal plant was demonstrated in several in vitro studies, using both rats and human models. Although the composition of this plant was identified, little is known about the pharmacological activity of most of the isolated substances. In this work, we present an evaluation of the rheological alterations in human blood by in vitro treatment with aqueous extracts (infusion and maceration) of B. forficata. Our results show that, in low concentrations, no hemolysis is observed, erythrocyte deformability and AChE enzyme activity decreased for the extract that received high temperature in their preparation. The analysis of the hemorheologic effects of the two different plant extracts can be considered a fundamental tool to assess their hemocompatibility and the possibility of using them to reverse some of the alterations observed in vascular processes, particularly in diabetes.
D. Kayal vizhi, K. Irulandi, V. Siva, P. Mehalingam and N. Nirmalkumar,DOI: 10.24214/IJGHC/HC/7/4/41925.
The present investigation assesses the antioxidant effect and quantitative phytochemical analysis of the leaf extracts of Eucalyptus globules and Syzygium cumini leaves. The methanolic leaf extracts Eucalyptus globules and Syzygium cumini were evaluated for antioxidant activity using DPPH radical scavenging. The results of the present study showed that the methanolic leaf extract of Eucalyptus globules which contains highest amount of phenolic compounds exhibited the greatest antioxidant activity. The occurrence of better antioxidant property mainly contribute to the reducing the radical molecule presence in the phenolic compounds
T.S Magili and I.B Bwatanglang,DOI: 10.24214/IJGHC/HC/7/4/40118.
In this study, Elemental Hierarchal Decision Tree’ was developed to aid in the selection of anti-diabetic medicinal plants species on the basis of elemental content preponderance. Instrumental neutron activation analysis (INAA) was used to investigate the bioaccumulation trends of 22 elements in 10 medicinal plants commonly used in Adamawa state, Nigeria for the treatment and management of diabetes mellitus (DM). From the results of the study the essential nutrients such as K, Na, Fe and Co are most effectively translocated by Leptadenia hastata with translocated factor (TF) = 1.51, 1.27, 1.90 and 2.83 respectively. Hymenocardia acida was found to be most effective for majority of the radioactive elements, Sm, Yb, Th, Lu and U with TF = 24.65, 33.46, 82.33 and 25.00 respectively. On the basis of tissue accumulation, the leave of Leptadenia hastata ranked highest in cumulative concentration of elements and Anogeissus leiocarpus ranked highest in cumulative concentration of elements in the stem bark sample. The root bark sample of Jathropha gossypiifolia was ranked highest in cumulative concentration of elements. On the whole, Ca, K and Mg (macro elements) and Cl, Fe, Zn and Mn (micro elements) are the most representatives of essential minerals found in the order of cumulative concentrations in all medicinal plants tissues investigated.
Shyamal K. Jash and Lalan Chandra Mandal,DOI: 10.24214/IJGHC/HC/7/3/36981
India is a gifted country with rich biodiversity and treasure of medicinal plants. From the ancient times various plants have been using for healthcare. Among them, very few were studied systematically so far. Lantana camara is a flowering ornamental and evergreen plant found throughout India. The plant has evoked a lot of interests among the researchers due to its diversified pharmaceutical potential. The Plant is reported to be used in traditional medicine system since very long time for the treatment of various ailments including itches, cuts, ulcers, swellings, bilious fever, cataract, eczema and rheumatism. In last few decades, scientists and researchers have investigated on different parts of the plants. In continuous investigations on this plant, it has been observed that various parts of the plant are used in the treatment of cold, headache, chicken pox, eye injuries, whooping cough, asthma, bronchitis and arterial hypertension. These studies established the therapeutic potential of Lantana camara in modern medicines and considered to be promising candidate for the drug discovery. The current review has deeper focus on Taxonomy, Geographical distribution, phytochemical studies, pharmacological activities and toxicology of Lantana camara.