Green open space is a facility provided by the city government for public use and public property. Apart from being a city greening and as a rainwater catchment area, green open space has a specific and very important function, namely as a means of social and cultural interaction for urban communities. This form of interaction can be in the form of family trips, sports, peer-to-peer meetings, etc. Even green open spaces are able to revive the small economy of the community, namely in the form of small-scale trade. The approach used in this research is a qualitative descriptive research approach because the author wants to describe or describe the facts or circumstances or symptoms that occur in the study. The techniques used in data collection are observation, interviews, and document analysis related to green open spaces. Secondary data sources were obtained from the Pulubala Urban Village Office, Kota Tengah District, Gorontalo City. The informants consisted of the Head of the Pulubala Urban Village, Kota Tengah District, Gorontalo City, the Head of the Gardening Division of the Gorontalo City Environmental Service, the Head of the Spatial Planning Division of the Gorontalo City Public Works and Public Housing Office and the Pulubala Housing Community. The results of this study indicate that The background of the construction of green open spaces in Pulubala housing is based on the absence of a place for people to carry out activities in the housing environment. The existence of green open space in Pulubala housing is very important to maintain the balance and harmony of this environment. The function of the green open space located in Pulubala housing can be used by the community to carry out activities and to interact with other people in the Pulubala housing complex. But seeing the activities that people do in green open spaces, there are still problems both in terms of physical conditions, usage, public awareness and in their management. The interaction and social relations of the Pulubala housing community can be seen with the level of harmony and intimacy between the people. In addition, the factors of interaction and social relations among the Pulubala housing community are influenced by not knowing each other between communities, work, and differences of opinion. Of these several factors, it can lead to a lack of interaction and social relations between communities in Pulubala housing.">">

Cadmium (Cd) is a well-known environmental single substance toxicant. Cadmium exposure results in the production of free radicals in cells which leads to the damage to DNA and also promotes neoplasmic progressions. Phyllanthus emblica (amla) commonly known as Indian gooseberry, is a globally well acknowledged medicinal plant. It possess several bioactive phytochemicals which showed anti-inflammatory, antitumor, anti-diabetic and anti-nephrotoxic activity. The present work was aimed to study the antioxidative effects of aqueous leaf extracts of amla against cadmium induced oxidative stress in cultured human peripheral blood lymphocytes  using  catalase, superoxide mutase (SOD) and lipid peroxidation assay (LPA) as biomarkers. Cadmium administration significantly increased the lipid peroxidation, SOD, catalase activity in peripheral blood lymphocytes in a dose dependent manner. Aqueous leaf extract of amla showed significant decrease in SOD, catalase and LPA levels. The present study suggests protective effects of amla leaf extract against cadmium mediated oxidative stress.">

Sniffing lead-containing substances phenomenon is widely spread among homeless children in Khartoum City. In this study, a total of 120 sniffers and 40 normal children as control were randomly selected to investigate the effect of sniffing lead-containing substances on the biochemical parameters of homeless adolescent in Khartoum City, Sudan. Measurements of lead (mg/dl), calcium (mg/dl), total protein (mg/dl), albumin (mg/dl), total bilirubin (mg/dl), direct bilirubin (mg/dl), indirect bilirubin (mg/dl), AST (U/L), ALT (U/L), cholesterol and triglyceride were investigated. Result indicated that all of the studied biochemical parameters were not significantly affected by age of sniffers, but some parameters such as lead, total bilirubin and indirect bilirubin were slightly increased with increasing sniffers age. Governmental authorities can help to control sniffing lead-containing substances through effective polices and enact laws to combat the practices.">

A series of 1,2,3-triazolo-piperazines compounds were synthesized and characterized by ¹HNMR, ¹³C NMR, IR, Mass spectroscopy and screened for anticancer activity using C6 Glioma cell lines. Among 15 compounds of triazole series, four of the compounds showed the most potent antiproliferative activity as well as good selectivity between cancer and normal cells. These compounds 1 (IX), 2 (VIII1), 3 (IX2) and 4 (VII2) exhibited good anti-proliferation activity with IC₅₀ values of 0.05µM against C6 glioma cell lines evaluated in vitro.

The present study deals with the removal of colour and reduction of certain substances from the textile dyeing industry effluent using iron oxide nanoparticles. Iron oxide nanoparticles were synthesized and characterized by using SEM, EDAX, FTIR., XRD, and VSM. Physico-chemical parameters of dyeing industry effluent such as pH, electrical conductivity, total solids, total dissolved solids, total suspended solids, hardness, sodium, potassium, calcium, magnesium,sulphate, chloride dissolved oxygen, BOD, COD, copper, nickel, and zinc, were estimated. The role of different quantities of iron oxide nanoparticles on the physicochemical parameters of Textile Dyeing Industry effluent such as colour, pH, electrical conductivity, COD, calcium, and magnesium was estimated after exposing the effluent for half an hour. SEM images of iron oxide nanoparticles were observed at 5 µm and 10 µm. Spherical shapes were observed. EDAX spectrum recorded on synthesized iron oxide nanoparticles was identified in 7 peaks. FT-IR spectrum of iron oxide nanoparticles was analyzed in the range of 500-4000 cm^-1 and spectral bands were observed. The synthesized iron oxide nanoparticles were confirmed by XRD and the crystal average size is 21 ± 82 nm. The synthesized iron oxide nanoparticles exhibit low saturation magnetization at 8.865 emu g^-1. All the parameters decreased with an increasing quantity of iron oxide nanoparticles. From the present study, it is concluded that 500mg of iron oxide nanoparticles removed colour and reduced the parameters pH, electrical conductivity, COD, calcium, and magnesium present in the textile dyeing industry effluent.">

The recognition of the loss of sensitivity of insect pests to several synthetic active ingredients is putting crop phytosanitary protection programs in difficulty. In order to exploit the different modes of action of the active compounds of natural pesticides for an effective and lasting control of pests, the aphicidal effect of extemporaneous mixtures of the essential oil of Ocimum canum and that of Ocimum basilicum L., two plants of the Togolese flora, was evaluated in vitro on Aphis gossypii. The tests were carried out in the laboratory according to the IRAC N° 1 Version 2 methodology. The results obtained showed that the essential oil of O. canum potentiates the action of the essential oil of O. basilicum, using small amounts of O. canum mixed with high amounts of O. basilicum. The inhibition ratios (IR) confirmed these results to be greater than 1 with doses below 4 µLm.L-1. The strong synergies demonstrated between the essential oils may allow the use of reduced doses of the essential oil of O. canum mixed with O. basilicum to ensure effective control of A. gossypii.">

The purpose of this work is to study the possibility of obtaining composite electrochemical coatings (CEC) with a copper matrix containing nanocarbon from cheap secondary raw materials with improved running ability. The optimal carbon concentration providing high-quality coatings with improved properties was established. The process of stability of suspensions (containing carbon material obtained from the shell of hazelnuts) in time in water, aqueous solutions of surfactants, and in a nickel-plating electrolyte after dispersion has been investigated. It was found that dispersing has a positive effect on the stability of aqueous suspensions. The addition of an ionic surfactant does not affect the stability of the suspension. Non-ionic surfactants increase the stability of the medium and electrolyte solutions sharply reduce the stability. The wear resistance of carbon-containing composite coatings was investigated. The wear of the CEC copper-carbon material depends on the concentration of carbon material inclusions in the matrix. The maximum wear resistance is achieved at a concentration of the second phase in a suspension of 0.04 g/L, with a carbon content in composite coatings of 6.53-8.06% (mass). It is established that the wear of the CEC is 1.5 times less than the wear of “clean” copper coating.

Telmisartan is an antihypertensive drug used for the treatment of high blood pressure. The monographs of European Pharmacopoeia (Ph. Eur.) and United States Pharmacopeia (USP) specify eight and six impurities respectively for its active pharmaceutical ingredient (API). The identification and synthesis of all impurities of pharmacopeia and others are well described in the literature, however, there is no report for KSM related impurity,1-Hydroxy-4-methyl-2propyl-1-H- benzoimidazole -6-carboxylic acid (N-Hydroxy impurity). The prospects to the formation and control of N-Hydroxy impurity in the synthesis of Telmisartan API, generating at significant levels during scale up are discussed in detail for the first time. The most plausible mechanism involved in the formation of this impurity has been proposed. The present work is vital to have a better control on the process and routine batch analysis to supply Telmisartan API free from N-Hydroxy impurity.